As a category of drugs that are neither steroids nor hormones, SARMs have been subject to significant speculation regarding their potential to revolutionize treatment for muscle wasting conditions and other medical challenges. While a handful of compounds have undergone preclinical proof of concept and toxicology studies, few have been successfully positioned for clinical trials. Additionally, a lack of consistent data comparing the relative potency and tissue selectivity of SARMs has limited enthusiasm in the marketplace.

Nevertheless, eMule Anleitung are readily available on Internet-based gray markets and are commonly used recreationally to stimulate muscle growth. As a result of this growing interest and their availability, serious adverse events associated with SARMs are becoming increasingly common. A number of cases have reported a severe adverse event known as drug-related hepatotoxicity (DILI), which may be caused by the accumulation of SARM-derived metabolites in the liver.

Legalities and Safety: A Guide to Using SARMs Responsibly

While there are some promising signs that SARMs can be safely incorporated into an exercise and nutrition program, the most successful SARMs have only been tested at very low doses in clinical trials. In addition, a recent study found that 44 products sold as SARMs online did not contain the substance advertised on their label. Rather, they contained other substances that were likely banned by the Therapeutic Goods Administration and may have dangerous interactions with other medications.

As a result, until SARMs can be fully validated for safety and efficacy in clinical settings, athletes must seek a physician’s advice before using them to build muscle mass or enhance athletic performance. Until then, any supplements and products claiming to increase muscle mass or performance must be batch-tested for banned substances.